Bias FX2 in Reaper (VST) - moving knobs in FX2 during playback has no effect

  • I am running Reaper 64bit Windows with Bias FX2 are a plugin (VST). Even in the simplest project, a single track of guitar, when I am playing back the track and I am trying to adjust my tone (swapping amps, adjust an effect, adjusting controls on an amp) I do not hear any change.

    When doing the exact same thing in Ableton Live 10, works as expected. Any thoughts here?

    Also doing this in Reaper with Guitar Rig 5 works as expected.